November 14, 2018 – Presented by Dr. Martin Dawes – Adverse drug reactions (ADRs) cause more deaths than diabetes. This global epidemic kills 1400 people every day, harms countless others, and costs $130 billion to the healthcare system in the US alone. One of the main drivers for ADRs is the need for health professionals to assess hundreds of facts when identifying safe and effective medications for an individual. For a patient who has five conditions, there are 1500 facts that need to be checked including interactions of genetics, other medications, disease state, and biophysical factors such as weight, kidney, and liver with drug options.
Genetic variations in particular account for a significant proportion of ADRs and ineffective prescriptions. Pharmacogenetic information helps clinicians identify the correct dose and drug for an individual but without a smart software application clinical implementation of pharmacogenetics is challenging. To overcome the challenge of fact checking, our research team developed a precision prescribing software that fits into the health care provider’s workflow and is capable of translating pharmacogenetics into easy-to-use medication options. The software has been used by patients and healthcare providers to generate hundreds of safe and effective medication options and is helping employers and benefit providers reduce health absenteeism cost.
At any one time eight percent of employees in the health system are off work. This is a major problem for health care organizations in providing a safe effective service. To enable employers and other organizations to see the benefit of providing precision prescribing and pharmacogenetics with a medication decision support software application, we have created a benefit calculator. This allows the organization to dynamically assess the potential advantage of implementing this solution. Implementing precision prescribing options improves outcomes and reduces adverse drug reactions, so that the rate of absenteeism can be significantly reduced.
Dr. Martin Dawes is a world expert in primary care who combines research and clinical practice with over 30 years of experience. Following the completion of his PhD, he helped develop a Masters program in Evidence Based Health Care. He has directed the UK Centre for Evidence-Based Medicine in Oxford and was the head of family practice at McGill University and the University of British Columbia. Dr. Dawes is the Chief Scientific Officer and Co-Founder of GenXys, a precision prescribing company. He is also a Professor of Family Medicine at the University of British Columbia (UBC).